SCHEMBL22200016

SCHEMBL22200016

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-n4c5ccccc5c5c6ccccc6c6c7ccccc7n(-c7ccccc7)c6c54)n3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.42
ATM Q13315 2/20 0.42
KDM4E B2RXH2 1/20 0.42
AVPR1A P37288 1/20 0.38
KMT2A Q03164 5/20 0.37
IL1R1 P14778 1/20 0.37
MEN1 O00255 4/20 0.36
HTT P42858 2/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.36
MAPK1 P28482 1/20 0.36
HSP90AA1 P07900 1/20 0.35
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14900857 0.97 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22200037 0.94 L3MBTL1 (0.44) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL17245563 0.93 L3MBTL1 (0.46) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL23741533 0.92 L3MBTL1 (0.38) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26420952 0.92 KMT2A (0.41) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26420953 0.92 KMT2A (0.41) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL24549928 0.92 KMT2A (0.41) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26420941 0.92 KMT2A (0.41) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL19998002 0.92 L3MBTL1 (0.42) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17123096 0.90 L3MBTL1 (0.41) L3MBTL1ATMKDM4EKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT L3MBTL1 80/4885ATM 2798/4885KDM4E 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.