SCHEMBL22200146

SCHEMBL22200146

C=C[Si](C)(CC(=C)C[Si](C)(C)C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24278420 0.79 MAPT (0.46) MAPTESR1ESR2
SCHEMBL8770161 0.74 MAPT (0.35) MAPTESR1ESR2
SCHEMBL11316901 0.72 MAPT (0.38) MAPTESR1ESR2
SCHEMBL1493150 0.67
SCHEMBL464990 0.65 ESR1 (0.41) MAPTESR1ESR2
SCHEMBL453982 0.64 NR1H2 (0.48) MAPTESR1ESR2
SCHEMBL2524118 0.64 ESR1 (0.39) MAPTESR1ESR2
SCHEMBL160355 0.64 ESR1 (0.39) MAPTESR1ESR2
SCHEMBL3317837 0.63 NR1H2 (0.37) MAPTESR1ESR2
SCHEMBL5995457 0.63 MAOA (0.47) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200220222-A1 NONAQUEOUS ELECTROLYTE, NONAQUEOUS ELECTROLYTE SECONDARY BATTERY, AND ENERGY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2020-07-09 US disclosed