Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 7/20 | 0.38 |
| ▸ | BCR | P11274 | 7/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201399 | 0.90 | MEN1 (0.37) | ABCB1ABCG2ABL1BCREGFR | |
| SCHEMBL22201260 | 0.87 | ABL1 (0.39) | PRKCAPRKCDABCG2ABL1BCR | |
| SCHEMBL22201287 | 0.87 | ABL1 (0.39) | PRKCAPRKCDABL1BCREGFR | |
| SCHEMBL22201288 | 0.87 | ABL1 (0.39) | PRKCAPRKCDABL1BCREGFR | |
| SCHEMBL22201267 | 0.87 | ABL1 (0.38) | PRKCALCKPRKCDABCG2ABL1 | |
| SCHEMBL22201292 | 0.86 | SYK (0.42) | ABCB1ABCG2EGFREPHA2KDR | |
| SCHEMBL22201328 | 0.85 | ABL1 (0.38) | PRKCAPRKCDABCG2ABL1BCR | |
| SCHEMBL22201526 | 0.84 | ABL1 (0.35) | PRKCAPRKCDABL1BCREGFR | |
| SCHEMBL22201522 | 0.84 | ROCK2 (0.39) | ABL1BCREGFRPDGFRBPDGFRA | |
| SCHEMBL22201366 | 0.84 | MAPT (0.39) | ABCB1ABCG2ABL1BCREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |