Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.39 |
| ▸ | BCR | P11274 | 7/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201288 | 0.90 | ABL1 (0.39) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201260 | 0.90 | ABL1 (0.39) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201402 | 0.89 | MEN1 (0.36) | ABL1BCRSRCP2RX3MEN1 | |
| SCHEMBL22201328 | 0.87 | ABL1 (0.38) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201277 | 0.87 | PRKCA (0.42) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201267 | 0.87 | ABL1 (0.38) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201522 | 0.86 | ROCK2 (0.39) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201366 | 0.86 | MAPT (0.39) | ABL1BCRSRCEGFRPRKACA | |
| SCHEMBL22201302 | 0.85 | SYK (0.44) | P2RX3MEN1KMT2APIK3CALMNA | |
| SCHEMBL22201526 | 0.85 | ABL1 (0.35) | ABL1BCRSRCEGFRPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |