Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201273 | 0.90 | SYK (0.37) | SYKP2RX3TGFBR1UBE2MDCUN1D1 | |
| SCHEMBL22201224 | 0.89 | P2RX3 (0.42) | SYKP2RX3TGFBR1LMNACYP1A2 | |
| SCHEMBL22201368 | 0.88 | SYK (0.45) | SYKP2RX3TGFBR1CYP1A2GRM4 | |
| SCHEMBL22201421 | 0.87 | SYK (0.36) | SYKP2RX3TGFBR1CYP1A2GRM4 | |
| SCHEMBL22201272 | 0.87 | ULK1 (0.36) | SYKP2RX3TGFBR1 | |
| SCHEMBL22201489 | 0.86 | SYK (0.37) | SYKP2RX3TGFBR1CYP1A2GRM4 | |
| SCHEMBL22201262 | 0.85 | RIPK2 (0.36) | P2RX3TGFBR1LMNATP53ALDH1A1 | |
| SCHEMBL22201366 | 0.84 | MAPT (0.39) | SYKLMNACYP1A2MAPTEGFR | |
| SCHEMBL22201226 | 0.84 | PRKCH (0.37) | SYKP2RX3TGFBR1CYP1A2GRM4 | |
| SCHEMBL22201586 | 0.84 | PRKCH (0.47) | SYKTGFBR1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |