Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 5/20 | 0.36 |
| ▸ | PIP4K2C | Q8TBX8 | 5/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PIP4K2B | P78356 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201607 | 0.89 | RIPK2 (0.39) | RIPK2KDRPIP4K2APIP4K2CTP53 | |
| SCHEMBL22201534 | 0.88 | PIK3CD (0.40) | RIPK2KDRPIP4K2APIP4K2CJAK2 | |
| SCHEMBL22201273 | 0.86 | SYK (0.37) | P2RX3ALDH1A1TSHRTGFBR1 | |
| SCHEMBL22201425 | 0.86 | P2RX3 (0.36) | P2RX3ALDH1A1JAK2TYK2JAK3 | |
| SCHEMBL22201224 | 0.85 | P2RX3 (0.42) | KDRP2RX3LMNATGFBR1 | |
| SCHEMBL22201281 | 0.85 | SYK (0.36) | P2RX3TP53ALDH1A1LMNATGFBR1 | |
| SCHEMBL22201322 | 0.85 | PIP4K2C (0.34) | PIP4K2APIP4K2CP2RX3PIP4K2BJAK2 | |
| SCHEMBL22201493 | 0.84 | ROCK2 (0.34) | P2RX3TGFBR1 | |
| SCHEMBL22201368 | 0.84 | SYK (0.45) | P2RX3ALDH1A1TGFBR1 | |
| SCHEMBL22201272 | 0.83 | ULK1 (0.36) | KDRP2RX3TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |