Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201366 | 0.86 | MAPT (0.39) | SYKCYP2C19 | |
| SCHEMBL22201327 | 0.86 | SYK (0.40) | SYKTRPV1PIK3CDULK1ULK2 | |
| SCHEMBL22201272 | 0.85 | ULK1 (0.36) | SYKTRPV1ULK1ULK2 | |
| SCHEMBL22201226 | 0.84 | PRKCH (0.37) | SYKKCNH2AURKB | |
| SCHEMBL22201586 | 0.84 | PRKCH (0.47) | SYKKCNH2AURKB | |
| SCHEMBL22201536 | 0.84 | ACP1 (0.36) | SYKCYP2C19ULK1ULK2 | |
| SCHEMBL22201423 | 0.84 | TRPV1 (0.41) | TRPV1ULK1ULK2 | |
| SCHEMBL22201271 | 0.84 | SYK (0.38) | SYKTRPV1ULK1ULK2 | |
| SCHEMBL22201323 | 0.84 | SYK (0.38) | SYKPIK3CGKCNH2CYP2C19AURKB | |
| SCHEMBL22201273 | 0.83 | SYK (0.37) | SYKCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |