Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201475 | 0.82 | PRKCH (0.47) | PRKCHPRKCEGRM4FGFR2FLT3 | |
| SCHEMBL22201469 | 0.80 | FGFR2 (0.62) | PRKCHPRKCEGRM4FGFR2FLT3 | |
| SCHEMBL22201381 | 0.79 | PRKCH (0.51) | PRKCHPRKCEGRM4FGFR2FLT3 | |
| SCHEMBL22201586 | 0.77 | PRKCH (0.47) | PRKCHPRKCESYKKCNH2AURKB | |
| SCHEMBL22201449 | 0.77 | PRKCH (0.51) | PRKCHPRKCEGRM4FGFR2FLT3 | |
| SCHEMBL22201452 | 0.77 | PRKCH (0.58) | PRKCHPRKCESYKLMNAHPGD | |
| SCHEMBL22201450 | 0.75 | PRKCH (0.51) | PRKCHPRKCEGRM4FGFR2FLT3 | |
| SCHEMBL22201642 | 0.74 | PRKCH (0.53) | PRKCHPRKCEFGFR2FLT3SYK | |
| SCHEMBL22201369 | 0.74 | LMNA (0.63) | PRKCHPRKCESYKCYP1A2LMNA | |
| SCHEMBL22201641 | 0.72 | RIPK2 (0.55) | PRKCHPRKCESYKTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |