Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.33 |
| ▸ | ABL1 | P00519 | 3/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201328 | 0.90 | ABL1 (0.38) | P2RX3ABL1BCRSRC | |
| SCHEMBL22201245 | 0.87 | SYK (0.42) | MEN1KMT2AROCK2P2RX3SRC | |
| SCHEMBL22201402 | 0.86 | MEN1 (0.36) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201401 | 0.86 | KDM4E (0.36) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201404 | 0.86 | P2RX3 (0.38) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201399 | 0.84 | MEN1 (0.37) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201400 | 0.84 | KMT2A (0.37) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201403 | 0.83 | ROCK2 (0.35) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201564 | 0.82 | RIPK1 (0.36) | KDM4EMEN1KMT2AROCK2P2RX3 | |
| SCHEMBL22201586 | 0.81 | PRKCH (0.47) | KDM4EMEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |