Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201326 | 0.86 | ULK1 (0.40) | ACP1ULK1ULK2TGFBR1CYP1A2 | |
| SCHEMBL22201485 | 0.86 | ULK1 (0.40) | ACP1ULK1ULK2TGFBR1P2RX3 | |
| SCHEMBL22201423 | 0.86 | TRPV1 (0.41) | ULK1ULK2 | |
| SCHEMBL22201271 | 0.86 | SYK (0.38) | ULK1ULK2TGFBR1P2RX3SYK | |
| SCHEMBL22201225 | 0.86 | TGFBR1 (0.38) | GRM4TGFBR1P2RX3SYKCYP1A2 | |
| SCHEMBL22201272 | 0.85 | ULK1 (0.36) | ULK1ULK2TGFBR1P2RX3SYK | |
| SCHEMBL22201368 | 0.84 | SYK (0.45) | GRM4TGFBR1P2RX3SYKCYP1A2 | |
| SCHEMBL22201622 | 0.84 | SYK (0.42) | ULK1ULK2SYKCYP2C19 | |
| SCHEMBL22201494 | 0.83 | JAK2 (0.36) | ULK1ULK2GRM4TGFBR1P2RX3 | |
| SCHEMBL22201586 | 0.83 | PRKCH (0.47) | TGFBR1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |