Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 16/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201636 | 0.71 | PRKCH (0.47) | PRKCHPRKCESYK | |
| SCHEMBL22201640 | 0.71 | PRKCH (0.52) | PRKCHPRKCESYK | |
| SCHEMBL22201639 | 0.69 | PRKCH (0.52) | PRKCHPRKCESYK | |
| SCHEMBL22201369 | 0.69 | LMNA (0.63) | PRKCHPRKCESYKABCG2 | |
| SCHEMBL22201450 | 0.68 | PRKCH (0.51) | PRKCHPRKCESYK | |
| SCHEMBL22201381 | 0.68 | PRKCH (0.51) | PRKCHPRKCESYKABCG2 | |
| SCHEMBL22201452 | 0.67 | PRKCH (0.58) | PRKCHPRKCESYKABCG2 | |
| SCHEMBL22201469 | 0.67 | FGFR2 (0.62) | PRKCHPRKCESYK | |
| SCHEMBL22201642 | 0.66 | PRKCH (0.53) | PRKCHPRKCESYKABCG2 | |
| SCHEMBL22201437 | 0.62 | PRKCH (0.56) | PRKCHPRKCESYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |