Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935091 | 0.90 | TGFBR1 (0.47) | TGFBR1SCN9AKMOPIK3R1PIK3CA | |
| SCHEMBL1934340 | 0.84 | TRPA1 (0.44) | TGFBR1SCN9APDE3BPDE3A | |
| SCHEMBL1936339 | 0.84 | TRPA1 (0.44) | TGFBR1SCN9AKMOPDE3BPDE3A | |
| SCHEMBL1935744 | 0.83 | TRPA1 (0.43) | TGFBR1SCN9AKMOPDE3BPDE3A | |
| SCHEMBL2218335 | 0.83 | TRPA1 (0.43) | TGFBR1PDE3BPDE3A | |
| SCHEMBL2221789 | 0.81 | ABL1 (0.40) | TGFBR1SCN9AKMO | |
| SCHEMBL1935060 | 0.81 | TGFBR1 (0.44) | TGFBR1PIK3R1PIK3CA | |
| SCHEMBL1935549 | 0.81 | ALOX5AP (0.40) | TGFBR1SCN9APDE3BPDE3A | |
| SCHEMBL1934823 | 0.81 | JAK2 (0.39) | TGFBR1SCN9AKMO | |
| SCHEMBL1934736 | 0.81 | KMO (0.46) | MPLGRIN2BGRIN1KMOPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332936-B1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | TGFBR1 2587/4885MPL 3986/4885SCN9A 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.