Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22203844 | 0.95 | GNAI3 (0.44) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL17170006 | 0.89 | CA12 (0.46) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL12204444 | 0.89 | CA12 (0.46) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL13784031 | 0.89 | CA12 (0.46) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL21782715 | 0.86 | DPP7 (0.39) | DPP7KMT2ARRM1GNAI3GNAO1 | |
| SCHEMBL23638723 | 0.81 | CYP2D6 (0.44) | DPP7CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL22171084 | 0.79 | PAOX (0.47) | CYP2D6CYP2C9CYP2C19KMT2ACA12 | |
| SCHEMBL22171086 | 0.79 | PAOX (0.47) | CYP2D6CYP2C9CYP2C19KMT2ACA12 | |
| SCHEMBL12204449 | 0.79 | USP2 (0.47) | DPP7KMT2ARRM1GNAI3GNAO1 | |
| SCHEMBL823169 | 0.78 | CYP2D6 (0.50) | DPP7CYP2D6CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-06-08 | — | — | US | disclosed |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-08-23 | — | — | US | disclosed |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | DPP7 1938/4885CYP2D6 946/4885CYP2C9 2287/4885 |
| US-20200216571-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | DPP7 1938/4885CYP2D6 946/4885CYP2C9 2287/4885 |
| US-11421044-B2 | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto | NOS2, NOS3, NOS1 | DPP7 1938/4885CYP2D6 946/4885CYP2C9 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.