SCHEMBL2220405

SCHEMBL2220405

Cc1cc2ncccc2c2nc(-c3ccccc3)c(-c3ccccc3)c(C)c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 5/20 0.41
TOP1 P11387 1/20 0.41
PDE10A Q9Y233 2/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CCR1 P32246 1/20 0.36
CCR8 P51685 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
MAT2A P31153 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20263744 0.82 CCR1 (0.48) DHODHTOP1PDE10ATSHRKDM4E
SCHEMBL4356640 0.79 TOP1 (0.41) TOP1KDM4EMEN1KMT2AALDH1A1
SCHEMBL992447 0.76 CCR1 (0.42) KDM4ECCR1CCR8ALDH1A1MAPT
SCHEMBL28622581 0.75 CCR1 (0.41) KDM4ECCR1CCR8ALDH1A1MAPT
SCHEMBL27734736 0.75 CCR1 (0.41) KDM4ECCR1CCR8ALDH1A1MAPT
Hydrochloric Acid SCHEMBL5050003 0.71 LMNA (0.46) TOP1KDM4EMEN1KMT2AMAPT
SCHEMBL20903641 0.70 CCR1 (0.46) DHODHTOP1PDE10AKDM4EMEN1
SCHEMBL5008334 0.69 ALDH1A1 (0.44) TSHRKDM4EMEN1KMT2ACCR1
SCHEMBL18704719 0.68 LMNA (0.53) TOP1KDM4EMEN1KMT2AALDH1A1
SCHEMBL8083514 0.68 PDE10A (0.64) TOP1PDE10ATSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747281-B1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AGAMATRIX INC (US) 2010-09-08 EP claimed
US-11175256-B2 Electrochemical assay device and related methods AGAMATRIX, INC. (US) 2021-11-16 US disclosed
US-10203298-B2 Electrochemical cell and method of making an electrochemical cell AGAMATRIX, INC. (US) 2019-02-12 US disclosed
EP-1756557-B1 METHOD OF MAKING AN ELECTROCHEMICAL CELL AGAMATRIX INC (US) 2017-03-15 EP disclosed
CN-103353475-B Electrochemical cell and the method producing electrochemical cell 埃葛梅崔克斯股份有限公司 2017-03-01 CN disclosed
CN-103954668-B Electrochemical cell and the method producing electrochemical cell 埃葛梅崔克斯股份有限公司 2016-11-23 CN disclosed
US-20160245776-A1 Electrochemical Cell and Method of Making an Electrochemical Cell AGAMATRIX, INC. (US) 2016-08-25 US disclosed
US-9329150-B2 Electrochemical cell and method of making an electrochemical cell AGAMATRIX, INC. (US) 2016-05-03 US disclosed
CN-102778484-B Electrochemical cell and method of making an electrochemical cell AGAMATRIX INC 2015-04-01 CN disclosed
US-20140262778-A1 Electrochemical Cell and Method of Making an Electrochemical Cell AGAMATRIX, INC. (US) 2014-09-18 US disclosed
EP-1892244-A1 Fluorene-based compound and organo-electroluminescent device using the same Samsung Electronics Co., Ltd. (KR) 2008-02-27 EP disclosed
CN-101014851-A Electrochemical cell and method for producing an electrochemical cell AGAMATRIX INC (US) 2007-08-08 CN disclosed
CN-1985001-A Electrochemical assay device and related methods AGAMATRIX INC (US) 2007-06-20 CN disclosed
EP-1756557-A1 ELECTROCHEMICAL CELL AND METHOD OF MAKING AN ELECTROCHEMICAL CELL AgaMatrix, Inc. (US) 2007-02-28 EP disclosed
US-20070029539-A1 LIGHT-EMITTING ELEMENT ARRAY AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-02-08 US disclosed
EP-1747281-A1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AgaMatrix, Inc. (US) 2007-01-31 EP disclosed
WO-2005113790-A1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AGAMATRIX, INC. (US) 2005-12-01 WO disclosed
WO-2005114159-A1 ELECTROCHEMICAL CELL AND METHOD OF MAKING AN ELECTROCHEMICAL CELL AGAMATRIX, INC. (US) 2005-12-01 WO disclosed
US-20050258036-A1 Electrochemical assay device and related methods AGAMATRIX, INC. (US) 2005-11-24 US disclosed
US-20050258035-A1 Electrochemical Cell and Method of Making an Electrochemical Cell AGAMATRIX, INC. (US) 2005-11-24 US disclosed