SCHEMBL5008334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL992447	0.91	CCR1 (0.42)	ALDH1A1SMN1; SMN2MAPTL3MBTL1CYP1A2
	SCHEMBL28622581	0.89	CCR1 (0.41)	ALDH1A1SMN1; SMN2MAPTL3MBTL1CYP1A2
	SCHEMBL27734736	0.89	CCR1 (0.41)	ALDH1A1SMN1; SMN2MAPTL3MBTL1CYP1A2
	SCHEMBL8693066	0.71	MEN1 (0.48)	ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL1133753	0.70	CCR1 (0.57)	ALDH1A1SMN1; SMN2MAPTL3MBTL1CYP3A4
	SCHEMBL6266381	0.70	L3MBTL1 (0.52)	ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL2220405	0.69	DHODH (0.41)	ALDH1A1MEN1KMT2AMAPTPOLB
	SCHEMBL9053958	0.69	CCR1 (0.56)	ALDH1A1SMN1; SMN2MAPTL3MBTL1CYP3A4
	SCHEMBL11942827	0.68	HSP90AA1 (0.55)	ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL8654916	0.67	CCR1 (0.61)	ALDH1A1SMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.