SCHEMBL992447

SCHEMBL992447

Cc1nc2c(c(C)cc3ncccc32)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.42
CCR8 P51685 2/20 0.42
NPC1 O15118 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HSP90AA1 P07900 1/20 0.42
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 3/20 0.38
PRMT5 O14744 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 1/20 0.37
NUDT1 P36639 1/20 0.37
BRD4 O60885 1/20 0.37
ATAD2 Q6PL18 1/20 0.36
PSMD14 O00487 1/20 0.36
COPS5 Q92905 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27734736 0.98 CCR1 (0.41) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL28622581 0.98 CCR1 (0.41) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL5008334 0.91 ALDH1A1 (0.44) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL1133753 0.78 CCR1 (0.57) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL6266381 0.77 L3MBTL1 (0.52) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL2220405 0.76 DHODH (0.41) CCR1CCR8NPC1LMNAALDH1A1
SCHEMBL9053958 0.76 CCR1 (0.56) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL11942827 0.76 HSP90AA1 (0.55) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL8654916 0.74 CCR1 (0.61) CCR1CCR8NPC1L3MBTL1HSP90AA1
SCHEMBL862236 0.72 NPC1 (0.54) CCR1CCR8NPC1L3MBTL1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112341501-B Tetranuclear nickel-based complex with tetramethyl phenanthroline as ligand, and synthesis method and photocatalysis application thereof 云南师范大学 2023-06-20 CN claimed
CN-115872998-A Preparation method of sildenafil and intermediate thereof 山东特珐曼药业有限公司 2023-03-31 CN claimed
CN-112341501-A Tetranuclear nickel-based complex with tetramethyl phenanthroline as ligand, and synthesis method and photocatalytic application thereof 云南师范大学 2021-02-09 CN claimed
CN-107325103-B A kind of electroluminescent organic material, preparation method and application 中节能万润股份有限公司 2019-08-20 CN claimed
CN-107325103-A A kind of electroluminescent organic material, its preparation method and application 中节能万润股份有限公司 2017-11-07 CN claimed
US-20120226041-A1 CATALYSTS AND BORONATE ESTERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-09-06 US claimed
EP-1747281-B1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AGAMATRIX INC (US) 2010-09-08 EP claimed
US-5225556-A Phenanthroline derivatives THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1993-07-06 US claimed
EP-0155135-B1 METHODS OF ASSAY SERONO DIAGNOSTICS LIMITED (GB) 1992-09-23 EP claimed
US-5077197-A Qualitative or quantitative assay of ligands in a sample SERONO DIAGNOSTICS LIMITED (GB) 1991-12-31 US claimed
EP-0155135-A2 Methods of assay SERONO DIAGNOSTICS LIMITED (GB) 1985-09-18 EP claimed
US-20260022139-A1 ANTIMICROBIAL AGENT THE UNIVERSITY OF SHEFFIELD (GB) 2026-01-22 US disclosed
EP-3947404-B1 ANTIMICROBIAL AGENT UNIV SHEFFIELD (GB) 2025-10-01 EP disclosed
US-12404291-B2 Antimicrobial agent THE UNIVERSITY OF SHEFFIELD (GB) 2025-09-02 US disclosed
WO-2025023769-A1 NOVEL SYNTHESIS METHOD OF 18F-RUCAPARIB 고려대학교 산학협력단 2025-01-30 WO disclosed
EP-1623969-A1 ALPHA-PENTAFLUOROETHYLACRYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Tosoh F- Tech Inc. (JP) 2006-02-08 EP disclosed
WO-2005113790-A1 ELECTROCHEMICAL ASSAY DEVICE AND RELATED METHODS AGAMATRIX, INC. (US) 2005-12-01 WO disclosed
WO-2005114159-A1 ELECTROCHEMICAL CELL AND METHOD OF MAKING AN ELECTROCHEMICAL CELL AGAMATRIX, INC. (US) 2005-12-01 WO disclosed
US-20050258035-A1 Electrochemical Cell and Method of Making an Electrochemical Cell AGAMATRIX, INC. (US) 2005-11-24 US disclosed
US-20050258036-A1 Electrochemical assay device and related methods AGAMATRIX, INC. (US) 2005-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226041-A1 CATALYSTS AND BORONATE ESTERS BCHE, BRI3BP, BRAP CCR1 857/4885CCR8 814/4885NPC1 1007/4885
US-12404291-B2 Antimicrobial agent C1S, AOC3, HAX1 CCR1 211/4885CCR8 739/4885NPC1 1077/4885
US-20260022139-A1 ANTIMICROBIAL AGENT LBR, ARG1, FPR1 CCR1 549/4885CCR8 2038/4885NPC1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.