Sugi Predict

Sugi Predict / Compounds / SCHEMBL2220955

SCHEMBL2220955

SCHEMBL2220955

Cc1ccc(S(=O)(=O)CNC=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 11/20 0.52
▸ CYP3A4 P08684 2/20 0.52
▸ CYP2C9 P11712 2/20 0.52
▸ CYP2C19 P33261 2/20 0.52
▸ MAPT P10636 4/20 0.51
▸ ADAM17 P78536 1/20 0.51
▸ TDP1 Q9NUW8 2/20 0.49
▸ TP53 P04637 1/20 0.49
▸ CTSK P43235 1/20 0.47
▸ KMT2A Q03164 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ TLR9 Q9NR96 1/20 0.45
▸ GAA P10253 2/20 0.45
▸ CYP1A2 P05177 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ HPGD P15428 1/20 0.43
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42
▸ MMP1 P03956 1/20 0.42
▸ MMP2 P08253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975244 0.84 ALDH1A1 (0.59) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL9595880 0.81 ALDH1A1 (0.58) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL8940953 0.80 ALDH1A1 (0.51) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL8940894 0.80 MAPT (0.50) ALDH1A1MAPTTDP1TP53KMT2A
SCHEMBL7148200 0.78 ALDH1A1 (0.57) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL3997583 0.77 ALDH1A1 (0.52) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL63945 0.77 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL420473 0.76 ALDH1A1 (0.55) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL21492212 0.75 ALDH1A1 (0.43) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL5974473 0.74 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819298-A Preparation method and application of p-toluenesulfonylmethyl isonitrile 北京富盛嘉华医药科技有限公司 2023-03-21 — — CN claimed
CN-113896664-A Preparation method of p-toluenesulfonylmethyl formamide 北京颖泰嘉和生物科技股份有限公司 2022-01-07 — — CN claimed
US-20100190768-A1 NOVEL FUSED PYROLE DERIVATIVE DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2010-07-29 — — US claimed
CN-100506805-C Process for producing 5-substituted oxazole compound and 5-substituted imidazole compound NIPPON SODA CO (JP) 2009-07-01 — — CN claimed
US-RE40795-E1 Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds NIPPON SODA CO., LTD. (JP) 2009-06-23 — — US claimed
EP-1930320-A1 NOVEL FUSED PYRROLE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2008-06-11 — — EP claimed
US-20070027324-A1 Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds NIPPON SODA CO., LTD. (JP) 2007-02-01 — — US claimed
US-7102010-B2 Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds NIPPON SODA CO., LTD. (JP) 2006-09-05 — — US claimed
EP-1371649-B1 PROCESS FOR PRODUCING 5-SUBSTITUTED OXAZOLE AND 1,5-DISUBSTITUTED IMIDAZOLE COMPOUNDS NIPPON SODA CO (JP) 2006-07-05 — — EP claimed
US-20040116711-A1 Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds NIPPON SODA CO., LTD. (JP) 2004-06-17 — — US claimed
CN-1500084-A Process for producing 5-substituted oxazole compound and 5-substituted imidazole compound �ձ�������ʽ���� 2004-05-26 — — CN claimed
EP-1371649-A1 PROCESS FOR PRODUCING 5-SUBSTITUTED OXAZOLE COMPOUNDS AND 5-SUBSTITUTED IMIDAZOLE COMPOUNDS NIPPON SODA CO., LTD. (JP) 2003-12-17 — — EP claimed
EP-0378046-B1 Process for the preparation of 3-phenyl-pyrrole derivatives CIBA GEIGY AG (CH) 1995-01-18 — — EP claimed
EP-0242001-B1 PROCESS FOR THE MANUFACTURE OF N-(SULFONYLMETHYL) FORMAMIDES AND SULFONYLMETHYLISOCYANIDES ROUSSEL-UCLAF (FR) 1991-03-06 — — EP claimed
CN-1009924-B Process for preparing N- (sulfonylmethyl) formamide GIST BROCADES N (NL) 1990-10-10 — — CN claimed
US-4958030-A Process for the preparation of 3-phenylpyrrole derivatives CIBA-GEIGY CORPORATION (US) 1990-09-18 — — US claimed
EP-0378046-A1 Process for the preparation of 3-phenyl-pyrrole derivatives CIBA-GEIGY AG (CH) 1990-07-18 — — EP claimed
US-4922016-A Process for the preparation of N-(sulfonylmethyl) formamide compounds GIST-BROCADES N.V. (NL) 1990-05-01 — — US claimed
CN-87102774-A N-(sulfonymethyl) methane amide preparation method — 1987-11-18 — — CN claimed
EP-0242001-A1 Process for the manufacture of n-(sulfonylmethyl) formamides and sulfonylmethylisocyanides ROUSSEL-UCLAF (FR) 1987-10-21 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027324-A1 Process for producing 5-substituted oxazole compounds and 5-substituted imidazole compounds DDT, TES, ALK ALDH1A1 1291/4885CYP3A4 92/4885CYP2C9 69/4885
US-20100190768-A1 NOVEL FUSED PYROLE DERIVATIVE NR3C1, NR3C2, NR0B1 ALDH1A1 4118/4885CYP3A4 274/4885CYP2C9 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.