Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220955 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3250372 | 0.79 | PKM (0.64) | ALDH1A1MMP13PKMMMP8KMT2A | |
| SCHEMBL7207056 | 0.77 | MMP13 (0.60) | ALDH1A1MAPTMMP13PKMMMP8 | |
| SCHEMBL8940894 | 0.76 | MAPT (0.50) | ALDH1A1MAPTMMP13MMP8KMT2A | |
| SCHEMBL6708168 | 0.75 | PKM (0.64) | ALDH1A1MMP13PKMMMP8MMP1 | |
| SCHEMBL1346537 | 0.74 | HTT (0.58) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9705169 | 0.74 | PKM (0.61) | ALDH1A1MMP13PKMMMP8KMT2A | |
| SCHEMBL5335393 | 0.73 | CA1 (0.61) | ALDH1A1MMP13PKMMMP8MMP1 | |
| SCHEMBL19214423 | 0.72 | ALDH1A1 (0.66) | ALDH1A1MMP13PKMMMP8KMT2A | |
| SCHEMBL14468640 | 0.72 | PKM (0.59) | ALDH1A1MMP13PKMMMP8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565470-A | HYPOTENSIVE OR ANTIARRHYTHMIA AGENTS, ALSO FOR TREATMENT OF ANGINA OR GLAUCOMA | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5340820-A | Useful for treatment of ocular diseases, angina pectoris, hypertension and arrhythmia | ELF SANOFI (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0382628-B1 | Aminoalkoxylphenyl derivatives, process for their preparation and compositions containing them | SANOFI ELF (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0382628-A1 | Aminoalkoxylphenyl derivatives, process for their preparation and compositions containing them | ELF SANOFI (FR) | 1990-08-16 | — | — | EP | disclosed |