Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22210777 | 0.86 | AURKB (0.42) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13701698 | 0.78 | CHRNB2 (0.59) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL319126 | 0.77 | ALDH1A1 (0.58) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18256949 | 0.74 | BCAT2 (0.56) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11434922 | 0.73 | ALDH1A1 (0.53) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10172579 | 0.72 | KAT6A (0.56) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6748722 | 0.71 | MAPT (0.61) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL320357 | 0.71 | TSHR (0.53) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL973933 | 0.69 | ALDH1A1 (0.61) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14357551 | 0.69 | ALDH1A1 (0.56) | KMT2AMAPTMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10710996-B2 | Pyrido-azaheterecydic compound and preparation method and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10710996-B2 | Pyrido-azaheterecydic compound and preparation method and use thereof | MET, MERTK, DMPK | KMT2A 885/4885MAPT 2878/4885MEN1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.