SCHEMBL2221183

SCHEMBL2221183

CCOc1ccc(O)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
HPGD P15428 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CALM1 P0DP23 1/20 0.44
LTA4H P09960 1/20 0.42
NPC1 O15118 1/20 0.42
MAPK1 P28482 1/20 0.42
TP53 P04637 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
GAA P10253 1/20 0.41
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3722551 0.85 HPGD (0.47) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL1697735 0.84 TSHR (0.44) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL11232859 0.83 MEN1 (0.41) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL13303485 0.83 KDM4E (0.49) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL11225125 0.82 F2 (0.56) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL3026188 0.81 CALM1 (0.51) MAPTHPGDKMT2AALDH1A1LMNA
SCHEMBL3724504 0.79 ALDH1A1 (0.46) MAPTHPGDKMT2AALDH1A1LMNA
SCHEMBL1847263 0.79 ALDH1A1 (0.58) MAPTHPGDTDP1L3MBTL1KMT2A
SCHEMBL1477520 0.79 PDE4A (0.49) KMT2AALDH1A1MEN1CALM1LTA4H
SCHEMBL1390954 0.78 MAPT (0.49) MAPTHPGDTDP1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2949655-B1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEM IND CO (JP) 2019-05-15 EP disclosed
US-9707551-B2 Reaction catalyst for cross-coupling and method for manufacturing aromatic compound HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2017-07-18 US disclosed
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2015-12-17 US disclosed
EP-2949655-A1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND Hokko Chemical Industry Co., Ltd. (JP) 2015-12-02 EP disclosed
EP-1775335-B9 Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2013-06-26 EP disclosed
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
EP-1775335-B1 Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2012-05-23 EP disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
WO-2010127208-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2010-11-04 WO disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
EP-1775335-A2 Organic lectroluminescent element IDEMITSU KOSAN COMPANY LIMITED (JP) 2007-04-18 EP disclosed
US-20060189828-A1 Organic electrolumescence device IDEMITSU KOSAN CO., LTD. (JP) 2006-08-24 US disclosed
EP-1666561-A1 Organic electroluminescent element IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-06-07 EP disclosed
US-6951693-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2005-10-04 US disclosed
US-20050038296-A1 Organic electrolumescence device IDEMITSU KOSAN CO., LTD. (JP) 2005-02-17 US disclosed
US-6743948-B1 HAVING DUAL CHRYSENE RINGS LINKED BY AMINO FUNCTIONALITY HAVING FURTHER ARYL AND ALKENYL SUBSTITUTION; EFFICIENCY; HEAT RESISTANCE; DURABILITY IDEMITSU KOSAN CO., LTD. (JP) 2004-06-01 US disclosed
US-20030072966-A1 Organic electrolumescence device IDEMITSU KOSAN CO., LTD. (JP) 2003-04-17 US disclosed
EP-1061112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAPT 3667/4885HPGD 3294/4885TDP1 2598/4885
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAPT 3667/4885HPGD 3294/4885TDP1 2598/4885
US-20030072966-A1 Organic electrolumescence device ABCC1, CCND1, JUND MAPT 2792/4885HPGD 1731/4885TDP1 1805/4885
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE ARL1, RIF1, EML4 MAPT 2504/4885HPGD 4721/4885TDP1 2733/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAPT 3667/4885HPGD 3294/4885TDP1 2598/4885
US-20050038296-A1 Organic electrolumescence device CHRM1, SCO2, CHRM4 MAPT 3881/4885HPGD 3214/4885TDP1 2609/4885
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND ALK, HRH4, HRH3 MAPT 4800/4885HPGD 3967/4885TDP1 4138/4885
US-20060189828-A1 Organic electrolumescence device SCO2, CHRM1, CHRM4 MAPT 3667/4885HPGD 3294/4885TDP1 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.