SCHEMBL1477520

SCHEMBL1477520

CCOc1ccc(O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.49
PDE4B Q07343 2/20 0.49
PDE4C Q08493 2/20 0.49
PDE4D Q08499 2/20 0.49
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
CALM1 P0DP23 1/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LTA4H P09960 1/20 0.45
TUBB1 Q9H4B7 1/20 0.45
ESR1 P03372 1/20 0.44
GAA P10253 1/20 0.43
MAOB P27338 1/20 0.43
TYR P14679 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960422 0.85 LTA4H (0.53) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL3026188 0.84 CALM1 (0.51) PDE4APDE4BPDE4CPDE4DCALM1
SCHEMBL19433111 0.83 LTA4H (0.48) CA12CA1CA2CA7CA9
SCHEMBL2319036 0.83 ALDH1A1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL19433121 0.82 LTA4H (0.52) ALDH1A1MEN1KMT2ALTA4HESR1
SCHEMBL3717467 0.81 ESR1 (0.54) PDE4APDE4BPDE4CPDE4DCA12
SCHEMBL3066802 0.81 TRPA1 (0.48) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL29756063 0.81 ESR1 (0.54) PDE4APDE4BPDE4CPDE4DCA12
SCHEMBL19433097 0.80 NR5A1 (0.55) MEN1KMT2ALTA4HESR1TYR
SCHEMBL2221183 0.79 MAPT (0.50) CALM1ALDH1A1MEN1KMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5151458-A Molding materials for liquid crystal resins BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US claimed
US-5143956-A Blends with low molecular weight liquid crystals BAYER AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
US-5102935-A With low molecular weight, liquid crystalline esters and/or ester amides BAYER AKTIENGESELLSCHAFT (DE) 1992-04-07 US claimed
EP-0464351-A2 Polycarbonate, polyestercarbonate and polyester moulding compositions with high melt flow BAYER AG (DE) 1992-01-08 EP claimed
EP-0444295-A1 Low-viscosity polyamide mouldings BAYER AG (DE) 1991-09-04 EP claimed
EP-0444292-A2 Easy fluoring polyamide moulding compositions BAYER AG (DE) 1991-09-04 EP claimed
EP-0398052-A2 Low-viscosity polyarylene sulfide mouldings BAYER AG (DE) 1990-11-22 EP claimed
EP-0359037-A2 Low-viscosity polyamide mouldings and mixtures BAYER AG (DE) 1990-03-21 EP claimed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 CN disclosed
EP-0232777-A2 Method of manufacturing parts of thermotropic liquid crystalline plastics with a defined orientation of the liquid crystal polymer molecule, and the parts so produced BAYER AG (DE) 1987-08-19 EP disclosed
US-4599395-A Thermotropic, aromatic polyesters having good mechanical strength, containing sulfonic acid groups or metal sulfonate groups a process for the production thereof BAYER AKTIENGESELLSCHAFT (DE) 1986-07-08 US disclosed
EP-0141320-A2 Thermotropic aromatic polyesters with high stiffness, process for their production and their use in the production of moulded articles, filaments, fibres and films BAYER AG (DE) 1985-05-15 EP disclosed
EP-0024499-B1 BIAXIALLY ORIENTED WHOLLY AROMATIC POLYESTER FILM AND PROCESS FOR PRODUCING SAME TEIJIN LIMITED (JP) 1984-03-07 EP disclosed
US-4333907-A Biaxially oriented wholly aromatic polyester film TEITIN LIMITED (JP) 1982-06-08 US disclosed
EP-0024499-A1 Biaxially oriented wholly aromatic polyester film and process for producing same TEIJIN LIMITED (JP) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C PDE4A 3452/4885PDE4B 4014/4885PDE4C 3500/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR PDE4A 4123/4885PDE4B 4400/4885PDE4C 3859/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 PDE4A 1354/4885PDE4B 1463/4885PDE4C 1257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.