SCHEMBL22216413

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23907332	0.88	MAPT (0.51)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL22207029	0.87	MAPT (0.50)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL22216178	0.78	MAPT (0.52)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL1303947	0.77	ALDH1A1 (0.39)	MAPTGAAHTTHSD17B10ALDH1A1
	SCHEMBL22216464	0.77	MAPT (0.40)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL22338336	0.76	MAPT (0.39)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL22323036	0.76	MAPT (0.39)	MAPTGAAPKMHTTHSD17B10
	SCHEMBL3367604	0.76	ALDH1A1 (0.39)	MAPTGAAPKMHSD17B10ALDH1A1
	SCHEMBL22207271	0.74	MAPT (0.37)	MAPTGAAHSD17B10TSHRALDH1A1
	SCHEMBL22323003	0.74	ALDH1A1 (0.40)	MAPTPKMALDH1A1POLBTLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.