Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221986 | 1.00 | ANPEP (0.48) | ANPEPERAP2SIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL2225811 | 0.84 | ANPEP (0.47) | ANPEPERAP2ADRB2MEN1KMT2A | |
| SCHEMBL2224042 | 0.84 | ANPEP (0.47) | ANPEPERAP2ADRB2MEN1KMT2A | |
| SCHEMBL4076046 | 0.83 | MMP12 (0.49) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL29657593 | 0.81 | OPRK1 (0.53) | SIGMAR1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL4897397 | 0.76 | ALDH1A1 (0.58) | ANPEPERAP2SIGMAR1CYP1A2CYP2C9 | |
| SCHEMBL22231651 | 0.75 | S1PR1 (0.42) | MEN1KMT2ATDP1S1PR2S1PR1 | |
| SCHEMBL10765117 | 0.75 | MAPT (0.42) | POLBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7195674 | 0.74 | MMP12 (0.50) | MEN1KMT2ASMN1; SMN2HTTHPGD | |
| SCHEMBL13675293 | 0.74 | ANPEP (0.54) | ANPEPERAP2SIGMAR1KCNH2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086566-A1 | METHOD OF RESOLUTION OF (RS) - 1, 1 ' - BI - 2 - NAPHTHOL FOR OBTAINING ENANTIOMERIC PURE I.E. (S) - (-) \" 1, 1 ' \"BI - 2 -NAPHTHOL AND/OR (R) - ( ) - 1, 1 ' - BI - 2 - NAPHTHOL VIA CO - CRYSTAL FORMATION WITH OPTICALLY ACTIVE DERIVATIVES OF GAMMA -AMINO ACIDS | LUPIN LIMITED (IN) | 2011-07-21 | — | — | WO | claimed |