Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222071 | 0.92 | S1PR1 (0.44) | S1PR1BRD4MAPK14 | |
| SCHEMBL2223599 | 0.92 | S1PR1 (0.47) | S1PR1BRD4MAPK14 | |
| SCHEMBL2222186 | 0.92 | S1PR1 (0.48) | S1PR1 | |
| SCHEMBL2223699 | 0.91 | S1PR1 (0.45) | S1PR1 | |
| SCHEMBL2224913 | 0.90 | S1PR1 (0.47) | S1PR1 | |
| SCHEMBL2222899 | 0.90 | S1PR1 (0.51) | S1PR1 | |
| SCHEMBL2223206 | 0.88 | S1PR1 (0.47) | S1PR1 | |
| SCHEMBL2225559 | 0.88 | S1PR1 (0.49) | S1PR1TRPA1 | |
| SCHEMBL2224142 | 0.86 | S1PR1 (0.51) | S1PR1 | |
| SCHEMBL2223727 | 0.85 | S1PR1 (0.47) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | claimed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | claimed |
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |