Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 6/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222186 | 0.92 | S1PR1 (0.48) | S1PR1SGMS2LMNAMAPTRXFP1 | |
| SCHEMBL2222541 | 0.91 | S1PR1 (0.51) | S1PR1SGMS2MAPTSCN9AAPP | |
| SCHEMBL2223599 | 0.88 | S1PR1 (0.47) | S1PR1LMNAMAPTRXFP1SCN9A | |
| SCHEMBL2222292 | 0.88 | S1PR1 (0.44) | S1PR1TRPA1 | |
| SCHEMBL2224919 | 0.87 | S1PR1 (0.49) | S1PR1SGMS2MAPTRXFP1CEPT1 | |
| SCHEMBL2223699 | 0.86 | S1PR1 (0.45) | S1PR1RXFP1APPMAOBCEPT1 | |
| SCHEMBL2222071 | 0.85 | S1PR1 (0.44) | S1PR1LMNAMAPTRXFP1SCN9A | |
| SCHEMBL2223727 | 0.85 | S1PR1 (0.47) | S1PR1LMNAMAPTRXFP1APP | |
| SCHEMBL14797108 | 0.85 | S1PR1 (0.70) | S1PR1LMNAMAPTRXFP1TTK | |
| SCHEMBL2222985 | 0.84 | S1PR1 (0.52) | S1PR1MAPTSCN9AMAOBCEPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |