SCHEMBL22222575

SCHEMBL22222575

CC1(C)OB(c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2cc(-c4ccc(-c5ccncc5)cc4)ccc2-3)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 8/20 0.49
LPL P06858 7/20 0.49
PDK2 Q15119 2/20 0.40
DGAT1 O75907 1/20 0.37
PDGFRB P09619 1/20 0.34
KDR P35968 1/20 0.34
CDC7 O00311 1/20 0.34
ROCK2 O75116 1/20 0.34
MAP4K4 O95819 1/20 0.34
PRKACA P17612 1/20 0.34
CDK2 P24941 1/20 0.34
GSK3B P49841 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
PIK3CA P42336 1/20 0.32
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
NOTUM Q6P988 1/20 0.32
P4HB P07237 1/20 0.32
IMPDH2 P12268 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22222520 1.00 LIPG (0.49) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL12781939 0.92 LIPG (0.59) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL2618790 0.92 LIPG (0.59) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL12781960 0.89 LIPG (0.62) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL20323184 0.88 LIPG (0.41) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL22222633 0.88 LIPG (0.46) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL13414973 0.87 LIPG (0.63) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL15937417 0.86 LIPG (0.51) LIPGLPLPRMT5WDR77P4HB
SCHEMBL12781953 0.86 LIPG (0.52) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL24257896 0.85 LIPG (0.57) LIPGLPLPDK2DGAT1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227647-A1 FLUORENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227647-A1 FLUORENE DERIVATIVE AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, LEF1 LIPG 2719/4885LPL 1843/4885PDK2 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.