SCHEMBL476484

SCHEMBL476484

O=C(c1ccccc1N1C(=O)C=CC1=O)C1CC(=O)N(O)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HSP90AA1 P07900 3/20 0.49
PKM P14618 3/20 0.49
ATM Q13315 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
CCR6 P51684 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MGLL Q99685 9/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 2/20 0.37
MITF O75030 1/20 0.37
AADAT Q8N5Z0 2/20 0.36
GOT1 P17174 1/20 0.36
KYAT1 Q16773 1/20 0.36
KYAT3 Q6YP21 1/20 0.36
FAAH O00519 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1061152 0.77 ALDH1A1 (0.48) TLR9ALDH1A1HSP90AA1PKMATM
SCHEMBL2222585 0.75 DDAH1 (0.51) ALDH1A1HSP90AA1PKMNPSR1CCR6
SCHEMBL229803 0.74 MGLL (0.47) ALDH1A1HSP90AA1PKMATMNPSR1
SCHEMBL1934695 0.74 MCL1 (0.46) ALDH1A1PKMGAAHTTSMN1; SMN2
Ammonia Solution, Strong SCHEMBL28851009 0.72 MCL1 (0.45) ALDH1A1PKMGAAHTTSMN1; SMN2
SCHEMBL183052 0.70 ALDH1A1 (0.71) TLR9ALDH1A1HSP90AA1PKMATM
SCHEMBL29364136 0.70 ALDH1A1 (0.71) TLR9ALDH1A1HSP90AA1PKMATM
SCHEMBL9240798 0.69 TLR9 (0.64) TLR9ALDH1A1HSP90AA1PKMATM
Hydrochloric Acid SCHEMBL6753288 0.69 ALDH1A1 (0.69) TLR9ALDH1A1HSP90AA1PKMATM
SCHEMBL10938557 0.69 ALDH1A1 (0.64) TLR9ALDH1A1HSP90AA1PKMATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP claimed
EP-2290100-B1 Kits for displacement Sandwich Immuno-PCR IRIS INT INC (US) 2014-02-19 EP claimed
EP-1704167-B1 A METHOD TO MAKE A PEPTIDE-CARRIER CONJUGATE WITH A HIGH IMMUNOGENICITY ANGELETTI P IST RICHERCHE BIO (IT) 2011-01-12 EP claimed
EP-1689846-A2 METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A NON-CLEAVABLE LINKER, SAID CONJUGATES, AND METHODS OF MAKING SAID CONJUGATES Immunogen, Inc. (US) 2006-08-16 EP claimed
EP-0941738-B1 Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria WYETH CORP (US) 2005-05-11 EP claimed
WO-2005037992-A2 METHOD OF TARGETING SPECIFIC CELL POPULATIONS USING CELL-BINDING AGENT MAYTANSINOID CONJUGATES LINKED VIA A NON-CLEAVABLE LINKER, SAID CONJUGATES, AND METHODS OF MAKING SAID CONJUGATES IMMUNOGEN, INC. (US) 2005-04-28 WO claimed
WO-1998057578-A1 APPLICATION OF ?13C-13C, 13C-15N, AND 13C-13C-15¿N ISOTOPICALLY ENRICHED PROTEINS AS TISSUE-DIRECTED IMAGE-ENHANCEMENT REAGENTS FOR MAGNETIC RESONANCE IMAGING UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) 1998-12-23 WO claimed
EP-0366770-B1 LIPOSOMES COUPLED TO HORMONES VESTAR INC (US) 1994-02-09 EP claimed
CN-122075735-A Therapeutic combinations comprising anti-FOLR 1 immunoconjugates 2026-05-26 CN disclosed
US-12624087-B2 CD155 variant immunomodulatory proteins and uses thereof ALPINE IMMUNE SCIENCES, INC. (US) 2026-05-12 US disclosed
US-12612446-B2 CTLA-4 variant immunomodulatory proteins and uses thereof ALPINE IMMUNE SCIENCES, INC. (US) 2026-04-28 US disclosed
EP-3349796-B1 THERAPEUTIC COMBINATIONS COMPRISING ANTI-FOLR1 IMMUNOCONJUGATES IMMUNOGEN INC (US) 2026-04-08 EP disclosed
EP-4717707-A2 VARIANT ICOS LIGAND IMMUNOMODULATORY PROTEINS AND RELATED COMPOSITIONS AND METHODS Alpine Immune Sciences, Inc. (US) 2026-04-01 EP disclosed
EP-4706777-A2 CD80 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF Alpine Immune Sciences, Inc. (US) 2026-03-11 EP disclosed
EP-0485471-A1 NATURAL HUMAN ANTI-GAMMA INTERFERON ANTIBODIES DETECTED AND PURIFIED BY SYNTHETIC PEPTIDES. TURANO ADOLFO (IT) 1992-05-20 EP disclosed
WO-1991002005-A1 NATURAL HUMAN ANTI-GAMMA INTERFERON ANTIBODIES DETECTED AND PURIFIED BY SYNTHETIC PEPTIDES TURANO ADOLFO (IT) 1991-02-21 WO disclosed
EP-0317804-A2 HIV peptides and methods for detection of HIV ABBOTT LABORATORIES (US) 1989-05-31 EP disclosed
EP-0275278-A1 PEPTIDE FRAGMENTS OF ORGAN-SPECIFIC NEOANTIGENS BIO-RAD LABORATORIES, INC. (US) 1988-07-27 EP disclosed
WO-1988000344-A1 PEPTIDE FRAGMENTS OF ORGAN-SPECIFIC NEOANTIGENS BIO-RAD LABORATORIES, INC. (US) 1988-01-14 WO disclosed
EP-0235391-A2 Peptides corresponding to antigenic and immunogenic determinants of major neutralizing proteins of rotaviruses The University of Saskatchewan (CA) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624087-B2 CD155 variant immunomodulatory proteins and uses thereof CD2BP2, CD2, LY96 TLR9 474/4885ALDH1A1 4268/4885HSP90AA1 1193/4885
US-12612446-B2 CTLA-4 variant immunomodulatory proteins and uses thereof CD2, CD274, IGSF11 TLR9 141/4885ALDH1A1 4442/4885HSP90AA1 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.