SCHEMBL2222759

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2222277	0.89	ADRB3 (0.33)	SLC6A2SLC6A4SLC6A3ADRB3AAK1
	SCHEMBL2223227	0.89	CHRM2 (0.34)	CHRM2CHRM1CHRM3SLC6A2SLC6A4
	SCHEMBL2222625	0.87	ALDH1A1 (0.36)	SLC6A2SLC6A4SLC6A3ADRB3HCRTR1
	SCHEMBL14553948	0.86	CHRM2 (0.35)	CHRM2CHRM1CHRM3SLC6A2SLC6A4
	SCHEMBL14649994	0.86	KDM4E (0.36)	SLC6A2SLC6A4SLC6A3ADRB3HCRTR1
	SCHEMBL2224651	0.86	SLC6A2 (0.38)	CHRM3SLC6A2SLC6A4SLC6A3ADRB3
	SCHEMBL15679901	0.86	KDM4E (0.36)	SLC6A2SLC6A4SLC6A3ADRB3AAK1
	SCHEMBL2223311	0.85	ADRB3 (0.37)	SLC6A2SLC6A4SLC6A3ADRB3AAK1
	SCHEMBL2222386	0.85	OPRM1 (0.39)	CHRM2CHRM1CHRM3SLC6A2SLC6A3
	SCHEMBL2224726	0.85	SLC6A9 (0.39)	SLC6A2SLC6A4SLC6A3ADRB3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.