SCHEMBL2224726

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223642	0.95	UBE2M (0.39)	SLC6A9SLC6A5KCNH2ADRB3UBE2M
	SCHEMBL2222100	0.95	UBE2M (0.39)	SLC6A9SLC6A5KCNH2ADRB3UBE2M
	SCHEMBL2223311	0.92	ADRB3 (0.37)	ADRB3UBE2MDCUN1D1ADRB2ADRB1
	SCHEMBL2222386	0.91	OPRM1 (0.39)	SLC6A9SLC6A5KCNH2UBE2MDCUN1D1
	SCHEMBL2224947	0.88	CCR5 (0.38)	ADRB3UBE2MDCUN1D1ACACBCCR5
	SCHEMBL2224442	0.88	CFTR (0.39)	ADRB3UBE2MDCUN1D1ACACBCCR5
	SCHEMBL15679901	0.88	KDM4E (0.36)	ADRB3UBE2MDCUN1D1SLC6A2SLC6A4
	SCHEMBL14649994	0.88	KDM4E (0.36)	ADRB3UBE2MDCUN1D1SLC6A2SLC6A4
	SCHEMBL2222666	0.87	ADRB3 (0.37)	ADRB3UBE2MDCUN1D1ADRB2ADRB1
	SCHEMBL2222558	0.86	SLC6A2 (0.38)	KCNH2SLC6A2SLC6A4SLC6A3ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.