SCHEMBL2223311

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2224947	0.95	CCR5 (0.38)	ADRB3ACACBKDM4EALDH1A1UBE2M
	SCHEMBL2222666	0.95	ADRB3 (0.37)	ADRB3ACACBKDM4EALDH1A1ADRB2
	SCHEMBL2224442	0.95	CFTR (0.39)	ADRB3ACACBKDM4EALDH1A1UBE2M
	SCHEMBL15679901	0.93	KDM4E (0.36)	ADRB3ACACBKDM4EALDH1A1SLC6A2
	SCHEMBL14649994	0.93	KDM4E (0.36)	ADRB3ACACBKDM4EALDH1A1SLC6A2
	SCHEMBL2224726	0.92	SLC6A9 (0.39)	ADRB3ACACBKDM4ESLC6A2SLC6A4
	SCHEMBL14632791	0.91	UBE2M (0.41)	ACACBKDM4EALDH1A1OPRK1UBE2M
	SCHEMBL2224421	0.89	PSMB5 (0.39)	KDM4EALDH1A1AAK1MCHR1
	SCHEMBL2223642	0.89	UBE2M (0.39)	ADRB3ACACBKDM4EALDH1A1ADRB2
	SCHEMBL2222558	0.88	SLC6A2 (0.38)	ACACBKDM4ESLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.