Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815058 | 0.84 | MAPT (0.59) | MAPTLMNAKDM4ERECQLALDH1A1 | |
| SCHEMBL29050822 | 0.84 | MAPT (0.59) | MAPTPOLBKDM4ERECQLALDH1A1 | |
| SCHEMBL7809430 | 0.84 | PLAAT3 (0.50) | POLBLMNATAAR1ALDH1A1HPGD | |
| SCHEMBL15571274 | 0.84 | LMNA (0.68) | POLBLMNATAAR1ALDH1A1HPGD | |
| SCHEMBL26975671 | 0.80 | LMNA (0.68) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL7438292 | 0.80 | KMT2A (0.60) | POLBLMNATAAR1ALDH1A1HPGD | |
| SCHEMBL26975666 | 0.78 | LMNA (0.48) | MAPTPOLBLMNAALDH1A1TACR1 | |
| SCHEMBL503819 | 0.78 | GABBR2 (0.76) | MAPTPOLBLMNAKDM4ERECQL | |
| SCHEMBL6045130 | 0.78 | KMT2A (0.79) | MAPTPOLBLMNATAAR1RECQL | |
| SCHEMBL7811226 | 0.77 | THRB (0.54) | MAPTLMNAALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086565-A1 | METHOD FOR PREPARATION OF ENANTIOMERICALLY ENRICHED AND/OR RACEMIC GAMMA-AMINO ACIDS | LUPIN LIMITED (IN) | 2011-07-21 | — | — | WO | disclosed |