SCHEMBL2224442

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2223311	0.95	ADRB3 (0.37)	UBE2MDCUN1D1CCR5ACACBKDM4E
	SCHEMBL2222666	0.92	ADRB3 (0.37)	UBE2MDCUN1D1ACACBCHRNB2CHRNB4
	SCHEMBL2224947	0.92	CCR5 (0.38)	UBE2MDCUN1D1CCR5ACACBKDM4E
	SCHEMBL14649994	0.92	KDM4E (0.36)	UBE2MDCUN1D1OPRM1ACACBKDM4E
	SCHEMBL15679901	0.92	KDM4E (0.36)	UBE2MDCUN1D1CCR5ACACBKDM4E
	SCHEMBL2222100	0.92	UBE2M (0.39)	UBE2MDCUN1D1OPRM1CCR5ACACB
	SCHEMBL14632791	0.92	UBE2M (0.41)	UBE2MDCUN1D1CCR5ACACBKDM4E
	SCHEMBL2224421	0.89	PSMB5 (0.39)	KDM4EALDH1A1AAK1
	SCHEMBL2223104	0.88	CCR5 (0.39)	CFTRUBE2MDCUN1D1OPRM1CCR5
	SCHEMBL2224726	0.88	SLC6A9 (0.39)	UBE2MDCUN1D1CCR5ACACBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.