Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 8/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224775 | 0.83 | S1PR1 (0.48) | S1PR1APPMAOBESR1ESR2 | |
| SCHEMBL14797044 | 0.75 | S1PR1 (0.52) | S1PR1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9932139 | 0.74 | SMN1; SMN2 (0.47) | MAOBNPC1RAB9AKDM4EHPGD | |
| SCHEMBL9931268 | 0.73 | PIK3CB (0.42) | APPMAOBNPC1RAB9AKDM4E | |
| SCHEMBL2222684 | 0.72 | S1PR1 (0.48) | S1PR1APPLMNAALOX5 | |
| SCHEMBL2222648 | 0.72 | MAOB (0.47) | APPMAOBESR1ESR2NPC1 | |
| SCHEMBL2225306 | 0.71 | S1PR1 (0.54) | S1PR1APPALDH1A1ALOX5 | |
| SCHEMBL15966895 | 0.71 | S1PR1 (0.54) | S1PR1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2221033 | 0.71 | S1PR1 (0.49) | S1PR1KDM4EALDH1A1HPGD | |
| SCHEMBL9966840 | 0.70 | GPR119 (0.35) | S1PR1MAOBNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729475-B1 | Carboxylic acid derivatives with an oxazolo[4,5-d]pyrimidine ring | SANOFI SA (FR) | 2015-06-10 | — | — | EP | disclosed |
| EP-2729475-B1 | Carboxylic acid derivatives with an oxazolo[4,5-d]pyrimidine ring | SANOFI SA (FR) | 2015-06-10 | — | — | EP | disclosed |
| US-8846692-B2 | Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8735402-B2 | Cycloalkyloxycarboxylic acid derivatives | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| US-8735402-B2 | Cycloalkyloxycarboxylic acid derivatives | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| US-8735402-B2 | Cycloalkyloxycarboxylic acid derivatives | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| EP-2729475-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2014-05-14 | — | — | EP | disclosed |
| EP-2523962-B1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | disclosed |
| US-20130079358-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2013-03-28 | — | — | US | disclosed |
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| WO-2013004828-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013004828-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | C3AR1, CCR2, C5 | S1PR1 233/4885CA1 2893/4885CA2 926/4885 |
| US-20130079358-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | OXGR1, EDNRA, EDF1 | S1PR1 129/4885CA1 2025/4885CA2 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.