Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192241 | 0.68 | TSHR (0.33) | KMT2AMAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL22235983 | 0.68 | GPR35 (0.36) | KMT2AMAPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL10654652 | 0.67 | SMN1; SMN2 (0.56) | HRH1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6180556 | 0.66 | ALDH1A1 (0.37) | KMT2AMAPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL1014815 | 0.65 | HTT (0.38) | HRH1RAB9AKMT2AMAPTHTT | |
| SCHEMBL27672566 | 0.64 | ALDH1A1 (0.36) | KMT2AMAPTHTTMAPK1L3MBTL1 | |
| SCHEMBL15056964 | 0.62 | HDAC3 (0.41) | RAB9AKMT2AMAPTMAPK1L3MBTL1 | |
| SCHEMBL28187319 | 0.61 | ALDH1A1 (0.41) | KMT2AMAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL4771331 | 0.60 | TSHR (0.35) | KMT2AMAPTHTTL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL29287371 | 0.60 | LMNA (0.36) | KMT2AMAPTHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089540-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2022-03-24 | — | — | US | disclosed |
| EP-3911309-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | Board Of Trustees Of Michigan State University (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150668-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089540-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | PDCD1, CD274, PDCD1LG2 | HRH1 2217/4885RAB9A 578/4885KMT2A 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.