Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17836900 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL4576653 | 0.89 | CYP2D6 (0.38) | HPGDMEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL4576655 | 0.84 | HPGD (0.36) | HPGDMEN1KMT2AHSD17B10CYP2D6 | |
| Hydrochloric Acid SCHEMBL1006196 | 0.82 | CYP2D6 (0.36) | KMT2ACYP2D6GAAL3MBTL1IDO1 | |
| Hydrochloric Acid SCHEMBL1007345 | 0.79 | SLC18A3 (0.31) | — | |
| SCHEMBL3575552 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL1004607 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL4523224 | 0.72 | KDM4E (0.31) | HPGDCYP2D6 | |
| Hydrochloric Acid SCHEMBL17836910 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL1007232 | 0.69 | HSD11B1 (0.35) | HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243098-B2 | Compound, polymer, cross-linked compound of polymer, and optical element including cross-linked compound | CANON KABUSHIKI KAISHA (JP) | 2016-01-26 | — | — | US | disclosed |
| US-8956691-B2 | Methods for manufacturing organic-inorganic composite particles, optical material, optical element and lens, and organic-inorganic composite particles | CANON KABUSHIKI KAISHA (JP) | 2015-02-17 | — | — | US | disclosed |
| US-20140163175-A1 | NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2014-06-12 | — | — | US | disclosed |
| US-20110177239-A1 | METHODS FOR MANUFACTURING ORGANIC-INORGANIC COMPOSITE PARTICLES, OPTICAL MATERIAL, OPTICAL ELEMENT AND LENS, AND ORGANIC-INORGANIC COMPOSITE PARTICLES | CANON KABUSHIKI KAISHA (JP) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163175-A1 | NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND | PCLAF, PCNA, SMC2 | CHRM2 4832/4885CHRM1 4822/4885HPGD 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.