Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898023 | 0.83 | HSD11B1 (0.34) | HSD11B1SLC18A3ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL4523224 | 0.82 | KDM4E (0.31) | KDM4ELMNAHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1007345 | 0.78 | SLC18A3 (0.31) | SLC18A3KDM4E | |
| Hydrochloric Acid SCHEMBL1006196 | 0.77 | CYP2D6 (0.36) | HSD11B1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL17836926 | 0.76 | TSHR (0.38) | SLC18A3ALDH1A1LMNAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL17836910 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1007082 | 0.74 | TACR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1006905 | 0.73 | KMT2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL17836900 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL2223643 | 0.69 | HPGD (0.32) | ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421702-B2 | Method for producing fluorine-containing olefin | AGC Inc. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-10358400-B2 | Method for producing olefin containing chlorine and fluorine | AGC Inc. (JP) | 2019-07-23 | — | — | US | disclosed |
| EP-3266758-B1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING OLEFIN COMPOUND | AGC INC (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-10252959-B2 | Method for producing fluorine-containing olefin compound | AGC Inc. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2018-03-29 | — | — | US | disclosed |
| EP-3266758-A1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING OLEFIN COMPOUND | Asahi Glass Company, Limited (JP) | 2018-01-10 | — | — | EP | disclosed |
| US-20170369402-A1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING OLEFIN COMPOUND | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-12-28 | — | — | US | disclosed |
| EP-3257885-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING POLYMER | Asahi Glass Company, Limited (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-20170335051-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING POLYMER | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-11-23 | — | — | US | disclosed |
| EP-3239126-A1 | METHOD FOR PRODUCING OLEFIN CONTAINING CHLORINE AND FLUORINE | Asahi Glass Company, Limited (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-20110177239-A1 | METHODS FOR MANUFACTURING ORGANIC-INORGANIC COMPOSITE PARTICLES, OPTICAL MATERIAL, OPTICAL ELEMENT AND LENS, AND ORGANIC-INORGANIC COMPOSITE PARTICLES | CANON KABUSHIKI KAISHA (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-1197509-B1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | ZEON CORP (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-2270063-A2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | NIPPON ZEON CO., LTD. (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-1275675-B1 | COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE | ZEON CORP (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6908970-B2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION (JP) | 2005-06-21 | — | — | US | disclosed |
| US-6815516-B2 | HEAT RESISTANCE, SOLVENT SOLUBILITY | ZEON CORPORATION (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20030050406-A1 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION | 2003-03-13 | — | — | US | disclosed |
| US-20030018138-A1 | Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these | ZEON CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1275675-A1 | COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE | Zeon Corporation (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-1197509-A1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | Nippon Zeon Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369402-A1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING OLEFIN COMPOUND | FOS, FOSB, CYP4F11 | HSD11B1 88/4885SLC18A3 3246/4885ALDH1A1 2126/4885 |
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | HSD11B1 229/4885SLC18A3 2037/4885ALDH1A1 607/4885 |
| US-10421702-B2 | Method for producing fluorine-containing olefin | FOS, CYP2F1, CYP4F11 | HSD11B1 229/4885SLC18A3 2037/4885ALDH1A1 607/4885 |
| US-10252959-B2 | Method for producing fluorine-containing olefin compound | FOS, FOSB, CYP4F11 | HSD11B1 97/4885SLC18A3 3006/4885ALDH1A1 2208/4885 |
| US-10358400-B2 | Method for producing olefin containing chlorine and fluorine | CYP2F1, CYP4F11, CYP4F2 | HSD11B1 153/4885SLC18A3 3268/4885ALDH1A1 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.