Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.55 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17303103 | 0.85 | TGFBR1 (0.65) | TGFBR1ADRB1ACVR1ACVR1B | |
| SCHEMBL18790712 | 0.85 | HTR1A (0.64) | TGFBR1ACVR1ACVR1BCHRNB2CHRNA4 | |
| SCHEMBL22236832 | 0.85 | CHRNB2 (0.67) | TGFBR1ADRB1ACVR1ACVR1BCHRNB2 | |
| SCHEMBL3453352 | 0.84 | HTR1A (0.66) | TGFBR1ADRB1CHRNB2CHRNA4HTR1A | |
| SCHEMBL6351651 | 0.84 | ADRB2 (0.61) | TGFBR1ACVR1ACVR1BCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3268024 | 0.83 | HTR1A (0.64) | TGFBR1ADRB1ACVR1ACVR1BCHRNB2 | |
| SCHEMBL11359435 | 0.80 | CHRNB2 (0.64) | ADRB1CHRNB2CHRNA4CHRNA1CHRNA7 | |
| SCHEMBL6351787 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRNA1CHRNA7 | |
| SCHEMBL6350059 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4HTR1AHTR7HTR2B | |
| SCHEMBL6348853 | 0.79 | CHRNB2 (0.61) | CHRNB2CHRNA4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | TGFBR1 1219/4885ADRB1 275/4885ACVR1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.