Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22924380 | 0.69 | PDE2A (0.30) | — | |
| SCHEMBL23638849 | 0.69 | PPARG (0.33) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL14824906 | 0.67 | — | — | |
| SCHEMBL257926 | 0.65 | ESR1 (0.41) | ADRA2AADRA2BADRA2C | |
| SCHEMBL21742988 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL23692800 | 0.65 | KDM4E (0.33) | — | |
| SCHEMBL24525250 | 0.62 | — | — | |
| SCHEMBL17432855 | 0.60 | LOXL2 (0.32) | — | |
| SCHEMBL24727549 | 0.60 | TP53 (0.35) | — | |
| SCHEMBL20096076 | 0.59 | PKM (0.33) | PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3372596-B1 | PREPARATION METHOD FOR TEDIZOLID, TEDIZOLID INTERMEDIATE, AND PREPARATION METHOD THEREFOR | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2020-07-22 | — | — | EP | disclosed |