Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22239082 | 0.89 | L3MBTL1 (0.34) | CYP2C19APPL3MBTL1MAPTALDH1A1 | |
| SCHEMBL22238934 | 0.88 | CYP2C19 (0.35) | CYP2C19APPL3MBTL1MAPTALDH1A1 | |
| SCHEMBL22239080 | 0.87 | CHKA (0.34) | CYP2C19APPCYP2C9GRM2 | |
| SCHEMBL22238933 | 0.86 | CASP3 (0.41) | CYP2C19APPL3MBTL1MAPTALDH1A1 | |
| SCHEMBL19636898 | 0.85 | MMP3 (0.34) | CYP2C19APPL3MBTL1MAPTALDH1A1 | |
| SCHEMBL25070374 | 0.83 | SLC10A2 (0.38) | GRM2 | |
| SCHEMBL22239077 | 0.81 | L3MBTL1 (0.33) | CYP2C19APPL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29336427 | 0.80 | — | — | |
| SCHEMBL21134114 | 0.80 | CYP11B1 (0.45) | CYP2C19APPL3MBTL1MAPK1POLB | |
| SCHEMBL21608566 | 0.79 | TMEM97 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |