SCHEMBL22245281

SCHEMBL22245281

CCO[Si](CCc1ccccc1F)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.47
AOC3 Q16853 1/20 0.43
IDO1 P14902 2/20 0.40
LMNA P02545 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.37
MAOB P27338 3/20 0.37
RIPK1 Q13546 1/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
MPO P05164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307120 0.87 CYP4F2 (0.37) TAAR1LMNAALDH1A1GAAMAPT
SCHEMBL11651264 0.80 TAAR1 (0.47) TAAR1ALDH1A1GAAKMT2A
SCHEMBL15733317 0.79 IDO1 (0.43) IDO1ALDH1A1MAOBRIPK1KDM4E
SCHEMBL3341059 0.79 CYP4F2 (0.33) ALDH1A1
SCHEMBL11600164 0.79 ALDH1A1 (0.40) TAAR1ALDH1A1KDM4EPOLB
SCHEMBL16669513 0.79 HTR1A (0.46) TAAR1IDO1MPO
SCHEMBL6561657 0.79
SCHEMBL1972956 0.77 TAAR1 (0.53) TAAR1AOC3IDO1
SCHEMBL15733788 0.76 DPP4 (0.34)
SCHEMBL2783361 0.76 MTNR1A (0.44) KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US claimed