SCHEMBL307120

SCHEMBL307120

CCO[Si](CCc1ccccc1CC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.37
CYP4A11 Q02928 2/20 0.37
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
TAAR1 Q96RJ0 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341059 0.91 CYP4F2 (0.33) CYP4F2CYP4A11ALDH1A1
SCHEMBL11651264 0.88 TAAR1 (0.47) ADRA2AADRA2BADRA2CTAAR1ALDH1A1
SCHEMBL22245281 0.87 TAAR1 (0.47) MAPTTAAR1KDM4EALDH1A1GAA
SCHEMBL11600164 0.87 ALDH1A1 (0.40) ADRA2BTAAR1KDM4EALDH1A1HPGD
SCHEMBL16669513 0.87 HTR1A (0.46) TAAR1
SCHEMBL6561657 0.87
SCHEMBL233930 0.86 ALDH1A1 (0.36) CYP4F2CYP4A11ALDH1A1HPGD
SCHEMBL1972956 0.85 TAAR1 (0.53) MTNR1AMTNR1BTAAR1
SCHEMBL2783361 0.84 MTNR1A (0.44) MTNR1AKDM4E
Ethylene SCHEMBL27576641 0.84 ALDH1A1 (0.38) KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739670-B1 SOL-GEL DERIVED COMPOSITIONS ABS MAT INC (US) 2023-10-11 EP claimed
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material ABS MATERIALS, INC. (US) 2021-01-05 US claimed
US-10391470-B2 Sol-gel derived compositions ABS MATERIALS, INC. (US) 2019-08-27 US claimed
US-20180360718-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL AQUANEX TECHNOLOGIES, LLC 2018-12-20 US claimed
US-20170028380-A1 SOL-GEL DERIVED COMPOSITIONS AQUANEX TECHNOLOGIES, LLC 2017-02-02 US claimed
US-20160324746-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL BRIGGS, ADAM 2016-11-10 US claimed
US-20160316804-A1 SOL-GEL ENCAPSULATED WATER-SOLUBLE ORGANIC LIQUIDS AND ORGANIC LIQUIDS AND METHOD OF USING SAME AQUANEX TECHNOLOGIES, LLC 2016-11-03 US claimed
US-20160271581-A1 METHOD FOR REMOVING MICROCYSTINS FROM AN AQUEOUS SOLUTION USING PARTICLES HAVING A REACTIVE THIOL FUNCTIONAL GROUP AQUANEX TECHNOLOGIES, LLC 2016-09-22 US claimed
US-9440869-B2 Sol-gel derived compositions ABS MATERIALS, INC. (US) 2016-09-13 US claimed
US-9144784-B2 Sorbent material and method for using the same ABS MATERIALS (US) 2015-09-29 US claimed
US-20110132845-A1 METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT AQUANEX TECHNOLOGIES, LLC 2011-06-09 US claimed
EP-1203032-A4 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INC (US) 2006-06-21 EP claimed
US-20040146766-A1 Proton electrolyte membranes, methods of making proton electrolyte membranes, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION 2004-07-29 US claimed
US-6559197-B2 Coating for siliceous surfaces comprising a hydrolyzable silicon compound such as a trialkoxysilane, halosilane, alkoxysilane and mixtures thereof and a photoacid catalyst; shelf life CORNING INCORPORATED 2003-05-06 US claimed
US-20030045600-A1 Coating for siliceous surfaces comprising a hydrolyzable silicon compound such as a trialkoxysilane, halosilane, alkoxysilane and mixtures thereof and a photoacid catalyst; shelf life CORNING INCORPORATED 2003-03-06 US claimed
JP-2002543039-A 2002-12-17 JP claimed
EP-1203032-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2002-05-08 EP claimed
US-6326416-B1 MIXTURE OF RADIATION CURABLE OLIGOMER AND ADHESION PROMOTER CORNING INCORPORATED 2001-12-04 US claimed
US-6316516-B1 FOR PRODUCING PROTECTIVE COATINGS, FOR ENCAPSULATING OPTICAL FIBERS TO ENHANCE DURABILITY, NON-DELAMINATING CORNING INCORPORATED 2001-11-13 US claimed
WO-2000066636-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2000-11-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10881598-B2 Method of using personal and home care compositions containing a sol-gel derived material FPR3, FPR1, MSN CYP4F2 4442/4885CYP4A11 3114/4885MAPT 3393/4885
US-20160324746-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL FPR3, FPR1, SGMS1 CYP4F2 4392/4885CYP4A11 3026/4885MAPT 3421/4885
US-20180360718-A1 METHOD OF USING PERSONAL AND HOME CARE COMPOSITIONS CONTAINING A SOL-GEL DERIVED MATERIAL FPR3, FPR1, SGMS1 CYP4F2 4437/4885CYP4A11 2961/4885MAPT 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.