SCHEMBL6561657

SCHEMBL6561657

[CH]c1ccccc1CC[Si](OCC)(OCC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307120 0.87 CYP4F2 (0.37)
SCHEMBL11651264 0.80 TAAR1 (0.47)
SCHEMBL3341059 0.79 CYP4F2 (0.33)
SCHEMBL22245281 0.79 TAAR1 (0.47)
SCHEMBL16669513 0.79 HTR1A (0.46)
SCHEMBL11600164 0.79 ALDH1A1 (0.40)
SCHEMBL1972956 0.77 TAAR1 (0.53)
SCHEMBL2783361 0.76 MTNR1A (0.44)
Ethylene SCHEMBL27576641 0.76 ALDH1A1 (0.38)
SCHEMBL339625 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994150-B1 Preparation of reinforced rubber GOODYEAR TIRE & RUBBER (US) 2004-03-24 EP claimed
US-6384127-B2 MIXTURE CONTAINING ORGANOSILANE DISULFIDE COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY 2002-05-07 US claimed
US-20010034392-A1 Preparation of reinforced rubber and use in tires THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-25 US claimed
EP-0994150-A1 Preparation of reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-19 EP claimed