Water

Water

SCHEMBL222477

O.O[Si](O)(O)O.[AlH3].[BaH2].[KH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL665405 0.94
Water SCHEMBL1743483 0.94
Water SCHEMBL222696 0.89
Water SCHEMBL221949 0.89
Water SCHEMBL665632 0.89
Fluoride SCHEMBL914182 0.88
Water SCHEMBL5542185 0.88
Water SCHEMBL664290 0.88
Water SCHEMBL664770 0.88
Water SCHEMBL226530 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3248953-A1 CEMENT COMPOSITION Halliburton Energy Services, Inc. (US) 2017-11-29 EP claimed
EP-2314555-A1 Zeolite-containing cement compostion Halliburton Energy Services, Inc. (US) 2011-04-27 EP claimed
WO-2006047812-A1 WATER TREATMENT HURSTWELL PTY LIMITED (AU) 2006-05-11 WO claimed
US-6989057-B2 Zeolite-containing cement composition HALLIBURTON ENERGY SERVICES, INC. (US) 2006-01-24 US claimed
EP-1428805-A1 Cement composition Halliburton Energy Services, Inc. (US) 2004-06-16 EP claimed
US-20040107877-A1 Zeolite-containing cement composition HALLIBURTON ENERGY SERVICES, INC. (US) 2004-06-10 US claimed
US-11634641-B2 Aerogel compositions for high temperature applications ASPEN AEROGELS, INC. (US) 2023-04-25 US disclosed
US-11549059-B2 Aerogel compositions with enhanced performance MIDCAP FUNDING IV TRUST 2023-01-10 US disclosed
US-11261380-B2 Aerogel compositions for high temperature applications MIDCAP FUNDING IV TRUST 2022-03-01 US disclosed
US-20210207032-A1 AEROGEL COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS ASPEN AEROGELS, INC. (US) 2021-07-08 US disclosed
US-20210198578-A1 AEROGEL COMPOSITIONS FOR HIGH TEMPERATURE APPLICATIONS ASPEN AEROGELS, INC. (US) 2021-07-01 US disclosed
US-11040307-B2 Method for removing contaminant from a fluid stream PURAFIL, INC. (US) 2021-06-22 US disclosed
US-20210079300-A1 AEROGEL COMPOSITIONS WITH ENHANCED PERFORMANCE ASPEN AEROGELS, INC. (US) 2021-03-18 US disclosed
EP-1569734-A1 HIGH CAPACITY SOLID FILTRATION MEDIA PURAFIL, INC. (US) 2005-09-07 EP disclosed
WO-2005063660-A2 METHOD FOR THE PURIFICATION OF PHARMACEUTICAL GRADE HFC-134A AND POLYMER GRADE HCFC-22 HONEYWELL INTERNATIONAL INC. (US) 2005-07-14 WO disclosed
US-20050133360-A1 Process for the purification of pharmaceutical grade HFC-134a and polymer grade HCFC-22 HONEYWELL INTERNATIONAL INC. 2005-06-23 US disclosed
EP-1428805-A1 Cement composition Halliburton Energy Services, Inc. (US) 2004-06-16 EP disclosed
US-20040107877-A1 Zeolite-containing cement composition HALLIBURTON ENERGY SERVICES, INC. (US) 2004-06-10 US disclosed
WO-2004047950-A1 HIGH CAPACITY SOLID FILTRATION MEDIA PURAFIL, INC. (US) 2004-06-10 WO disclosed
WO-2002099824-A2 NANOTUBE DEPOSITION ON ADSORBENTS IN WATER MAKER HEAT PUMP ZORNES DAVID A (US) 2002-12-12 WO disclosed