Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223206 | 0.92 | S1PR1 (0.47) | S1PR1APPCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2222292 | 0.90 | S1PR1 (0.44) | S1PR1 | |
| SCHEMBL2223699 | 0.89 | S1PR1 (0.45) | S1PR1APPCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2223599 | 0.88 | S1PR1 (0.47) | S1PR1MAPTAPPCETPCEPT1 | |
| SCHEMBL2222541 | 0.87 | S1PR1 (0.51) | S1PR1MAPTAPPCYP1A2CYP3A4 | |
| SCHEMBL2222899 | 0.86 | S1PR1 (0.51) | S1PR1MAPTAPPCYP1A2CYP3A4 | |
| SCHEMBL2222186 | 0.85 | S1PR1 (0.48) | S1PR1MAPTAPPCYP1A2CYP3A4 | |
| SCHEMBL14797022 | 0.85 | S1PR1 (0.68) | S1PR1MAPTALDH1A1PKMCETP | |
| SCHEMBL2222588 | 0.85 | S1PR1 (0.52) | S1PR1MAPTAPPCYP1A2CYP3A4 | |
| SCHEMBL2222985 | 0.85 | S1PR1 (0.52) | S1PR1MAPTCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |