SCHEMBL22249382

SCHEMBL22249382

Clc1cc(-c2ccc(-c3cc4ccccc4c4ccccc34)cc2)nc(-c2ccccc2)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
LMNA P02545 2/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
CYP11B1 P15538 1/20 0.45
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
ALDH1A1 P00352 5/20 0.45
HPGD P15428 5/20 0.45
MAPT P10636 4/20 0.45
NTSR1 P30989 1/20 0.45
ACACA Q13085 2/20 0.43
MAPK1 P28482 1/20 0.43
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AURKA O14965 1/20 0.42
AURKB Q96GD4 1/20 0.42
MPI P34949 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22274622 0.92 LMNA (0.43) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL31398855 0.90 LMNA (0.46) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL23802655 0.90 LMNA (0.46) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL17412415 0.90 LMNA (0.49) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL17412410 0.89 LMNA (0.51) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL17412390 0.89 KDM4E (0.51) KDM4ELMNAHSP90AA1HSP90AB1CYP11B1
SCHEMBL19009513 0.89 MEN1 (0.56) KDM4ELMNACYP11B1MEN1KMT2A
SCHEMBL29730457 0.88 MAOB (0.49) KDM4ELMNACYP11B1MEN1KMT2A
SCHEMBL14725234 0.88 MEN1 (0.54) KDM4ELMNACYP11B1MEN1KMT2A
SCHEMBL22249515 0.85 KDM4E (0.47) KDM4ELMNAHSP90AA1HSP90AB1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11374177-B2 Compound and organic light emitting device comprising the same SOULBRAIN CO., LTD. (KR) 2022-06-28 US disclosed
US-20220085298-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE LT MATERIALS CO., LTD. (KR) 2022-03-17 US disclosed
WO-2020153758-A1 COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE 엘티소재주식회사 2020-07-30 WO disclosed
US-20200235309-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SOULBRAIN CO., LTD. (KR) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220085298-A1 COMPOUND, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE ALDH1A2, OXER1, AOX1 KDM4E 3291/4885LMNA 4848/4885HSP90AA1 4295/4885
US-11374177-B2 Compound and organic light emitting device comprising the same CRY1, CRY2, AOX1 KDM4E 3615/4885LMNA 3561/4885HSP90AA1 4826/4885
US-20200235309-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, AOX1 KDM4E 3615/4885LMNA 3561/4885HSP90AA1 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.