Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017880 | 0.88 | SIGMAR1 (0.40) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL11090 | 0.82 | SIGMAR1 (0.49) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL20665988 | 0.81 | DPP4 (0.36) | MTNR1AMTNR1BKMT2ACYP2C19CYP2D6 | |
| SCHEMBL24276406 | 0.79 | SIGMAR1 (0.57) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL9891794 | 0.78 | SIGMAR1 (0.60) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL23866596 | 0.76 | SIGMAR1 (0.38) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL24333751 | 0.76 | SIGMAR1 (0.38) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL12413657 | 0.75 | SIGMAR1 (0.57) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL9891910 | 0.75 | SIGMAR1 (0.43) | SIGMAR1BCHEMTNR1AMTNR1BNQO2 | |
| SCHEMBL12017883 | 0.73 | TDP1 (0.38) | MTNR1AMTNR1BKMT2ADPP4PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231570-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231570-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | ADORA2A, ADORA3, ADORA1 | SIGMAR1 1575/4885BCHE 4381/4885MTNR1A 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.