SCHEMBL22255331

SCHEMBL22255331

c1ccc(-c2ccc3cc(-c4ccc(N(c5ccc(-c6cccc7cccc(-c8ccccc8)c67)cc5)c5cccc6oc7ccccc7c56)cc4)ccc3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.34
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
HCRTR1 O43613 1/20 0.33
CRHR1 P34998 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ANO1 Q5XXA6 1/20 0.32
PLA2G10 O15496 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HSD17B1 P14061 2/20 0.32
HSD17B2 P37059 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAOB P27338 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22255310 0.97 PLA2G2A (0.33) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL24901204 0.96 HSD17B1 (0.33) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL22837461 0.94 PLA2G2A (0.37) PLA2G2APLA2G4ACASP3SENP7SENP6
SCHEMBL22255329 0.94 PGR (0.36) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL22837471 0.94 BACE1 (0.33) PLA2G2APLA2G4ACRHR1CA12CA1
SCHEMBL26556933 0.94 PGR (0.34) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL22255288 0.93 CA12 (0.36) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL22255365 0.93 CA12 (0.36) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL23180733 0.93 PLA2G2A (0.36) PGRPLA2G2APLA2G4ACASP3SENP7
SCHEMBL24841359 0.93 PLA2G2A (0.36) PGRPLA2G2APLA2G4ACRHR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC18A2, SLC18A1, MAOA PGR 1261/4885PLA2G2A 4061/4885PLA2G4A 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.