Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042813 | 0.81 | SYK (0.40) | SYKPIK3CDPIK3CAMAPK13MAPK9 | |
| SCHEMBL24287892 | 0.77 | MAPK9 (0.50) | SYKMAPK8MAPK10HTR1AMAPK9 | |
| SCHEMBL14871556 | 0.75 | CDK2 (0.57) | SYKKCNH2SCN5ASCN9ACHRNA7 | |
| SCHEMBL29641671 | 0.74 | PIK3CD (0.49) | PIK3CDPIK3CA | |
| SCHEMBL17700440 | 0.73 | CHRNA7 (0.53) | PIK3CDCHRNA7 | |
| SCHEMBL1554844 | 0.73 | RAB9A (0.52) | SYKKCNH2SCN5ASCN9AIKBKB | |
| SCHEMBL16820278 | 0.70 | SYK (0.55) | SYKCDK2GSK3BMAPK14KDR | |
| SCHEMBL12615927 | 0.69 | PIK3CD (0.36) | MAPK8MAPK10PIK3CDPIK3CA | |
| SCHEMBL12696158 | 0.69 | PIK3CD (0.36) | MAPK8MAPK10PIK3CDPIK3CA | |
| SCHEMBL10284715 | 0.69 | MAP4K4 (0.43) | SYKPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020147739-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |