Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 16/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | GPR39 | O43194 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042813 | 0.76 | SYK (0.40) | PIK3CDPIK3C3 | |
| SCHEMBL14029983 | 0.75 | HRH4 (0.54) | CHRNA7HRH4HRH3NUDT1 | |
| SCHEMBL9169741 | 0.73 | HRH4 (0.52) | CHRNA7HRH4HRH3NUDT1 | |
| SCHEMBL16844971 | 0.73 | HRH4 (0.52) | CHRNA7HRH4HRH3PIK3CDPIK3C3 | |
| SCHEMBL22256859 | 0.73 | SYK (0.37) | CHRNA7PIK3CD | |
| SCHEMBL2852000 | 0.73 | KDM4E (0.44) | CHRNA7PIK3CD | |
| SCHEMBL13819906 | 0.72 | RXRA (0.36) | HRH3PIK3CDNUDT1 | |
| SCHEMBL24287892 | 0.72 | MAPK9 (0.50) | HRH4 | |
| SCHEMBL14004971 | 0.71 | HRH4 (0.50) | CHRNA7HRH4HRH3PIK3CDPIK3C3 | |
| SCHEMBL12932877 | 0.71 | HRH4 (0.50) | HRH4HRH3NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031799-B1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9776962-B2 | Aromatic compounds with GPR40 agonistic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| EP-3031799-A1 | AROMATIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-15 | — | — | EP | disclosed |
| US-20160115128-A1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115128-A1 | AROMATIC COMPOUND | GLP1R, GPR119, GPR39 | CHRNA7 2405/4885HRH4 669/4885HRH3 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.