Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852000 | 0.81 | KDM4E (0.44) | SYKPIK3CDPIK3CA | |
| SCHEMBL22256859 | 0.81 | SYK (0.37) | SYKPIK3CDPIK3CAMAPK14MAPK13 | |
| SCHEMBL15360081 | 0.81 | HTR1A (0.43) | PIK3C3PIK3CDPIK3CAPIK3CGMAPK14 | |
| SCHEMBL24287892 | 0.80 | MAPK9 (0.50) | SYKMAPK9 | |
| SCHEMBL1554844 | 0.76 | RAB9A (0.52) | SYK | |
| SCHEMBL17700440 | 0.76 | CHRNA7 (0.53) | PIK3C3PIK3CD | |
| SCHEMBL14871556 | 0.75 | CDK2 (0.57) | SYKPIK3C3AURKAAURKB | |
| SCHEMBL12500190 | 0.75 | CREBBP (0.41) | PIK3C3MAPK14FLT3 | |
| SCHEMBL8222078 | 0.75 | CREBBP (0.41) | PIK3C3MAPK14FLT3 | |
| SCHEMBL16273403 | 0.74 | HRH4 (0.46) | MAPK14MAPK13MAPK9MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912975-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |